Estrogen, Prostate, and Testosterone Acupuncture Cancer

Dr. John Lee stated estrogen can be the angel of life as well as the angel of death. When estrogen is metabolized abnormally, it can change the gene expression and alter significant intracellular signaling sequences that market abnormal cellular development and endothelial harm by creating vasoconstriction and producing cholesterol that is high. Thus too much estrogen can be a vulnerable DNA damaging (genotoxic) carcinogen & activate tumor-cell activators. For females, abnormally metabolized estrogen is able to cause uterus, breast and ovarian cancer; for males, prostate cancer. The latest article published in Molecular Cell Endocrinology in 2012 explained that testosterone can be changed to estradiol by aromatase in the fat cells, prostate cells, endothelial cells and breast cells. Dr. Bosland MC of U. of Illinois at Chicago did an experiment in which estradiol is used to the rats. When he did so, prostate cancer incidence markedly enhanced and even a quick program of estrogen treatment resulted in a high likelihood of prostate cancer.

Fourty years back, prostate cancer was generally more common in older people. By the age of 80, over 50 % of males had an enlarged prostate. But a majority of older males do not die of prostate cancer, because they don’t have imbalanced estrogen and testosterone levels. Certain males develop prostate cancer, while others don’t. This relies upon how the testosterone is metabolized. The testosterone could be metabolized to 5alpha-dihydrotestosterone which can’t be aromatized to estrogen and hardly induces prostate cancer. On the flip side, if too much testosterone is converted by an enzyme known as aromatase into estrogen, it may result in prostate cancer. Therefore it’s not testosterone itself but just how it is metabolized that causes prostate cancer. Estrogen receptors are conveyed in the prostate and also is likely to mediate which direction the testosterone may be metabolized. In the rat prostate, DNA injury is able to end up from estrogen treatment; this phenomenon can manifest prior to cancer growth and at precisely a similar place. Masayoshi Hiramatsu et al. recommended in a book called Prostate that overexpression of aromatase, possibly attributable to irregular gene regulation, might result in abnormal estrogen production in situ and play a role in the induction or maybe advancement of human prostatic disorders.

The main reason more and more younger men clinically determined to have benign prostate enlargement and prostate cancer while in the forties of theirs or maybe fifties is simply because as a culture, we eat much more highly processed food or perhaps simple sugars every morning, that may be converted into fat as a result of our sedentary life style. Simple sugars can cause an insulin surge, which causes inflammation. Far more fat means much more testosterone which can be changed into estrogen by aromatase. An abnormal level of estrogen, anxiety, deficiency of exercise as well as inflammation in concert can flip on poor gene expression. Consuming alcohol often may not only trigger impotence due to lowered levels of testosterone, but in addition increase activity of aromatase abnormally, that may lead to much more intracellular estrogen production from testosterone.

How does acupuncture help prevent or treat prostate cancer? For starters, acupuncture can balance your immune function to reduce typical inflammation, and that is closely related with cancer development. Second, acupuncture can alter the way you metabolize by boosting your digestive and thyroid function. When you consume specific food items, instead of saving all of the energy as excess fat, Go now you make a lot more heat and energy to let your body work much more efficiently- less fat and a lot less estrogen means a reduced amount of gene mutation. Last, acupuncture is able to reduce stress improving your sleep, reducing anxiety and enhancing natural killer-cell activity, which is critical during chemo- and radiation therapy treatment. Fourth, acupuncture assist your body create more feel good hormones, like GABA, dopamine and serotonin, thus you don’t need to drink alcohol to feel great and unwind.